Multi-cellular movements are found in various phenomena such as embryogenesis, cancer diseases, wound healing, and metabolism. While key genes and proteins differ by phenomenon, multi-cellular movements commonly follow mechanics. What are the mechanics that govern multicellular movement?
In the shaping of living organisms, individual cells interact in a multimordal way. To understand the complex phenomenon, we combine stem cell organoid experiments, which reproduce 3D structures of embryonic tissues in vitro, and mechanics-based simulations, which predict realistic 3D dynamics of cells.
Our approach integrates microscopic behaviors found at the molecular and cellular levels to predict the macroscopic shaping at the tissue and organ levels. In the bottom-up manner, we aim to provide a comprehensive understanding of multi-cellular system across a wide range of scales as a single system.
Okuda Lab, Nano Life Science Institute,
Kakuma-machi, Kanazawa 920-1192, Japan
Natural Science and Technology Hall2 6F room 2B613，2B620
satokuda AT staff.kanazawa-u.ac.jp